It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil eye ex Plaquenil hair growth Hydroxychloroquine sulfate Plaquenil® is prescribed for the treatment of rheumatoid arthritis, discoid and systemic lupus erythematosus, and other predominantly autoimmune diseases. Use of this systemic antimalarial drug has been associated with retinotoxic effects that can produce visual acuity and visual field loss. Lab Test Considerations Monitor CBC and platelet count periodically throughout therapy. May cause decreased RBC, WBC, and platelet counts. Ifseveredecreasesoccurthatarenotrelatedtothediseasepro-cess,hydroxychloroquineshouldbediscontinued. PotentialNursingDiagnoses RiskforinfectionIndications ChronicpainIndications Implementation Hydrocodone is a substrate for CYP2D6. Hydroxychloroquine is a moderate inhibitor of CYP2D6. Halogenated Anesthetics Major Avoid coadministration of hydroxychloroquine and halogenated anesthestics. Hydroxychloroquine increases the QT interval and should not be administered with other drugs known to prolong the QT interval. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine nursing considerations Hydroxychloroquine Side Effects Common, Severe, Long Term., Avoiduse Pedi Long-termuse hydroxychloroquine hye-drox-ee. Plaquenil vomitingCombination of sulfasalazine hydroxychloroquine and leflunomide for raHow to cleanse body from plaquenil toxicity Administration. Give drug with meals or milk to reduce incidence of GI distress. Give antacids and laxatives at least 4 h before or after hydroxychloroquine. Store at 15°–30° C 59°–86° F unless otherwise directed. HYDROXYCHLOROQUINE SULFATE. Plaquenil hydroxychloroquine sulfate dose, indications.. Hydrochlorothiazide Nursing Considerations, Side Effects, and.. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Pregnancy Considerations. Hydroxychloroquine can be detected in the cord blood at delivery in concentrations similar to those in the maternal serum Costedoat-Chalumeau 2002. In animal reproduction studies with chloroquine, accumulation in fetal ocular tissues was observed and remained for several months following drug elimination from the. Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine is also used.