Plaquenil guidelines for eye monitoring 2016

Discussion in 'Canada Drug' started by Globalzru, 28-Feb-2020.

  1. IDr Moderator

    Plaquenil guidelines for eye monitoring 2016


    Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating.

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    Aug 30, 2011 Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. My Take on New Ocular Screening Guidelines for Plaquenil By Sergio Schwartzman, MD 12 October 2016 A recent article published by the American Academy of Ophthalmology AAO presented new recommendations for screening of patients being managed with hydroxychloroquine HCQ. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.

    Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area).

    Plaquenil guidelines for eye monitoring 2016

    Retinal Physician - New Screening Guidelines for., My Take on New Ocular Screening Guidelines for Plaquenil.

  2. Hydroxychloroquine 200mg twice a dy
  3. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2.

    • Hydroxychloroquine Plaquenil Toxicity and..
    • Hydroxychloroquine Plaquenil.
    • Hydroxychloroquine And Chloroquine Screening 2016 AAO..

    Screening guidelines were updated this year, with some pertinent changes for our profession to note. Cumulative dose is no longer a risk factor, but more of a tool in the screening of our patients. To date, there are no data demonstrating that monitoring blood levels of HCQ is useful in dosing 34 HCQ to prevent retinal toxicity. 35 36 In addition to dose and duration of therapy, other factors must be considered when prescribing 37 HCQ and making recommendations about monitoring. Plaquenil and eye exams allie_bf posted For the last few years, my rheumagologist and opthamologist have disagreed on the frequency for eye exams my opthamologist says every year is sufficient, but my rheumatologist still insists every 6 months is what should be done.

     
  4. IncedsIconi XenForo Moderator

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine - FDA prescribing information, side effects. Alfa Aesar Chloroquine diphosphate salt, 98% Fisher Scientific Chloroquine MedlinePlus Drug Information
     
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    Hydroxychloroquine Dosage Guide with Detailed Hydroxychloroquine dosage information for adults and children. Includes dosages for Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria Prophylaxis and more; plus renal, liver and dialysis adjustments.

    Plaquenil User Reviews for Rheumatoid Arthritis at