Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells. Hydroxychloroquine effects on blood sugar Does plaquenil cause dark urine Does plaquenil make you sleepy Plaquenil confusion Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Pregnancy. Chloroquine has not been shown to have any harmful effects on the fetus when used for malarial prophylaxis. Small amounts of chloroquine are excreted in the breast milk of lactating women. However, because this drug can be safely prescribed to infants, the effects are not harmful. Pregnancy. One of the advantages of mefloquine is the fact that this is the only drug that can be taken during pregnancy when traveling to chloroquine-resistant areas. It is officially recommended for the 2nd and 3rd trimesters of pregnancy. Limited data also suggest that its use during the first trimester is safe. Both drugs may be needed for a complete cure and to prevent the return of infection (relapse). In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in other body tissues. Chloroquine contraindicated pregnancy Aralen Chloroquine Uses, Dosage, Side Effects., Chloroquine - Wikipedia What is retinopathy hydroxychloroquineChloroquine resistance transporterPlaquenil ulcerative colitis Safety of hydroxychloroquine in pregnant patients with connective tissue diseases a study of one hundred thirty-three cases compared with a control group. Costedoat-Chalumeau N1, Amoura Z, Duhaut P, Huong DL, Sebbough D, Wechsler B, Vauthier D, Denjoy I, Lupoglazoff JM, Piette JC. Safety of hydroxychloroquine in pregnant patients with.. Prophylaxis of Malaria - PubMed Central PMC. Chloroquine - StatPearls - NCBI Bookshelf. Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. Both methotrexate and leflunomide are contraindicated should not be used in women who are lactating. 2 Hydroxychloroquine and chloroquine are excreted into breast milk in small amounts and have been deemed safe by the American Academy of Pediatrics. 1,2. Biologics Chloroquine and mefloquine are the drugs of choice for pregnant women for destinations with chloroquine-sensitive and chloroquine-resistant malaria, respectively. Doxycycline is contraindicated because of teratogenic effects on the fetus after the fourth month of pregnancy.