Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality. Hydroxychloroquine arthritis Plaquenil and lupus anticoagulant User Reviews for Plaquenil to treat Systemic Lupus Erythematosus. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Original Article from The New England Journal of Medicine — Chronic Discoid Lupus Erythematosus — Treatment with Daraprim and Chloroquine Diphosphate Aralen Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids. Treatment of discoid lupus erythematosus with chloroquine PDF Successful treatment of discoid lupus erythematosus., Chronic Discoid Lupus Erythematosus — Treatment with Daraprim. Aao plaquenil ppp Oral thalidomide has increasingly been accepted as a treatment for cutaneous lupus erythematosus CLE, including DLE lesions, that have not responded to other treatments. Stevens RJ, Andujar C, Edwards CJ, et al. Thalidomide in the treatment of the cutaneous manifestations of lupus erythematosus experience in sixteen consecutive patients. Discoid lupus erythematosus - Treatment algorithm BMJ.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Discoid lupus erythematosus Symptoms and treatment of.. The treatment of discoid cutaneous lupus erythematosus was, until recently, very unsatisfactory. The disease not infrequently persists for many years, with intermittent exacerbations and partial remissions unrelated to any particular type of treatment. The only measure of regular value has been. Immunofluorescence of immunoglobulin G, immunoglobulin M, immunoglobulin A, and complement demonstrates a positive lupus band test. This occurs predominantly in the basement membrane and is found in the clinically uninvolved non–sun-exposed skin. Treatment for discoid lupus includes steroids and antimalarial drugs such as hydroxychloroquine. Discoid lupus erythematosus DLE is a form of lupus that mainly affects your skin. DLE is different from systemic lupus erythematosus SLE, the most common form of lupus, which can affect any part of the body.