I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Chloroquine solution storage Chloroquine combination therapy If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few months, but it can take up to six months for full effects. Stop taking the medicine and. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. We study how severe was Withdrawal syndrome, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil from sources other than FDA, and is updated regularly. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Plaquenil side effects when stopping Stopping plaquenil. DailyStrength, Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil and calcium citrate Guys, Are there side effects to stopping Plaquenil? If so, what? How soon after do you feel the effects of Sarcoidosis? Michele. Side effects to Stopping Plaquenil. - Sarcoidosis - Inspire. Withdrawal syndrome in Plaquenil how severe and when it was.. Will you have Withdrawal syndrome with Plaquenil - eHealthMe. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Lawchick my name is chellety and yes i have had horrbile side effects with the plaquenil they say it is suppose to be the best medication you can use for lupus but i was getting symptoms of that of a diabetes patient like gout in my toe, it was horrible pain and burning OMG, sounds weird but i stop taking the plaquenil and stuck to predisone.