Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil method of action Is hydroxychloroquine a nsaid Factors associated with hydroxychloroquine toxicity include the following Maintenance dose greater than 5 mg/kg/d based on real weight most critical risk Daily dose greater than 400 mg Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some. Hydroxychloroquine and Chloroquine have a similar dose related risk assessment. 10mg / kg is potentially toxic. Increasing mortality is expected at doses 30mg / kg. 5 grams in adults is fatal without intervention. Children Ingestion of just one tablet can be fatal in the under 6 year. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine toxicity Hydroxychloroquine-Induced Retinal Toxicity - American Academy of., Plaquenil Side Effects Common, Severe, Long Term - Plaquenil and ivf Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Chloroquine and Hydroxychloroquine • LITFL • Toxicology Library Toxicants. Chloroquine and Hydroxychloroquine Toxicity Practice.. Hydroxychloroquine toxicity Disease Entity. Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity. Diagnosis. For retinopathy, patients should be asked about poor central vision. Management. At the first signs of retinal toxicity, hydroxychloroquine should be stopped. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Plaquenil toxicity isn’t even in the top 10, or the top 100” if you’re looking at incidence, he said. “It’s a pretty rare thing.” Nevertheless, he urged doctors to master the Academy’s new guidelines, because the effects from chloroquine and hydroxychloroquine, when they do occur, are severe and often irreversible.