Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Why is the drug hydroxychloroquine Can hydroxychloroquine cause a lupus type rash What blood test are needed while on plaquenil Clinical Guidelines RCOphth Clinical Guidelines. The aim of College Clinical Guidelines is to identify the best medical evidence, set standards of patient care and ensure patient safety, providing a benchmark for outcomes within which high quality Ophthalmology can be practiced in the UK health service. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Hydroxychloroquine has been used relatively safely in pregnancy. The risks of stopping treatment should be weighed against the small possible risk to the unborn child. 2 Breast feeding is contraindicated.* *Local guidelines currently in development Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Hydroxychloroquine guidelines uk HYDROXYCHLOROQUINE SULFATE Drug BNF content published., Hydroxychloroquine MedlinePlus Drug Information Can hydroxychloroquine be crushedHydroxychloroquine in rheumatoid arthritis mechanism of actionPlaquenil qt intervalPlaquenil and tums Annual screening is recommended in all patients who have taken hydroxychloroquine for greater than 5 years; Annual screening may be commenced before 5 years of treatment if additional risk factors for retinal toxicity exist, such as concomitant tamoxifen therapy, impaired renal function eGFR less than 60 mL/minute/1.73 m 2 or high-dose therapy greater than 5 mg/kg/day of hydroxychloroquine sulfate. HYDROXYCHLOROQUINE SULFATE Drug BNF content published by NICE. Hydroxychloroquine gp guidelines 2008 - uk. Recommendations on Screening for Chloroquine and.. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of the initial. As per national, regional and local guidelines, to ensure that the patient/carer has received counselling and understands the therapy, its benefits, limitations, continued monitoring where applicable, Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.