Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Imuran plaquenil together What is the mode of action of chloroquine Instructions for taking chloroquine The use of Plaquenil may cause a severe flare of psoriasis. It can be effective at relieving the symptoms associated with psoriatic arthritis, and it may help. Dec 7, 2017. Additional skin-directed treatment options for drug-related psoriasis follows the conventional psoriasis. Plaquenil-induced erythroderma. Psoriasis patches can range from a few spots of dandruff-like scaling to major eruptions that cover large areas. Most types of psoriasis go through cycles, flaring for a few weeks or months, then subsiding for a time or even going into complete remission. There are several types of psoriasis. These include Plaque psoriasis. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil induced psoriasis Plaquenil Side Effects Common, Severe, Long Term -, Psoriasis - Symptoms and causes - Mayo Clinic Pharmacy hydroxychloroquine Most patients continue HCQ therapy in the long term, but ∼3% discontinue HCQ because of adverse cutaneous reactions. We now report a marked increase in the number of cutaneous reactions to HCQ over the last year, which apparently coincided with a change in formulation by the manufacturer. Increased cutaneous reactions to hydroxychloroquine.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Drugs That Can Trigger or Worsen Psoriasis. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Psoriasiform Drug Eruption and Drug-Provoked Psoriasis “Psoriasiform drug eruption” is a broad term referring to a heterogeneous group of disorders that clinically and/or histologically simulate psoriasis at some point during the course of the disease. 6 A psoriasiform eruption is used also to describe a histological reaction pattern, which exhibits presence of cellular infiltration. The management of these patients is difficult, as psoriasis benefits from sun exposure, which is harmful in LE, and systemic corticosteroids, indicated in LE, may produce severe psoriasis rebounds. It is known that antimalarial drugs that are helpful in LE are contraindicated in psoriasis 1.