Corticosteroid therapy should be instituted if the patient has clinically significant renal disease. Use immunosuppressive agents, particularly cyclophosphamide, azathioprine, or mycophenolate mofetil, if the patient has aggressive proliferative renal lesions, as they improve the renal outcome. Quinine plaquenil Taking plaquenil while on iron supplements Lupus nephritis is diagnosed through urine and blood tests and a kidney biopsy. Urine Test Your health care professional uses a urine sample to look for blood and protein in your urine. Kasitanon N, et al. Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis. Lupus. 2006;156366-70 Non-proliferative class I, II, V, or VI lupus nephritis PICO question Systemic lupus erythematosus SLE is a chronic, multisystem, inflammatory disorder of autoimmune etiology, occurring predominantly in young women. Common manifestations may include arthralgias and arthritis, Raynaud phenomenon, malar and other rashes, pleuritis or pericarditis, renal or CNS involvement. Calcineurin inhibitors, especially tacrolimus, have demonstrated benefit in lupus nephritis. Immunosuppressives can also be used if the patient has an inadequate response or excessive sensitivity to corticosteroids. Lupus nephritis and plaquenil Current Therapies for Lupus Nephritis, KDIGO GN Guideline update – Evidence summary Lupus nephritis Plaquenil for apdPlaquenil for raynaud'Chloroquine and breast cancerSide effects hydroxychloroquine sulfate 200 mgChloroquine effective against malaria Apr 14, 2007 In their Seminar on systemic lupus erythematosus SLE; Feb 17, p 587,1 David D'Cruz and colleagues make little mention of hydroxychloroquine as a treatment option. Hydroxychloroquine in systemic lupus erythematosus - The Lancet. Systemic Lupus Erythematosus SLE - Musculoskeletal and.. Lupus nephritis - Symptoms and causes - Mayo Clinic. Learn about the wide-ranging effects of hydroxychloroquine Plaquenil® in the treatment of lupus dosing, benefits, side effects and rare complications of this commonly prescribed medication. Summary Lupus nephritis is found among people who take Plaquenil, especially for people who are female, 20-29 old, have been taking the drug for 6 - 12 months, also take medication Cellcept, and have Pain. Is anyone else in Plaquenil and Zoloft? I’m on both and recently discovered that there is a major contraindication potential to prolong the QT interval your heart rhythm to using them together. I’m on both and recently discovered that there is a major contraindication potential to prolong the QT interval your heart rhythm to using them.