I took plaquenil for a while and it helped to reduce the duration/severity of the flairs, but I still had them. Both these drugs can take up to 3 months to begin to work. Plaqenil didn't stop my flare ups, but did ease some of the symptoms. It might also be worth checking what brand you have, as there are many posts on here about adverse reaction to a cheaper brand. Hydroxychloroquine pancreatic cancer Non aqueous titration of chloroquine What is the drug hydroxychloroquine used for What is plaquenil Azathioprine Imuran Imuran is an anti-inflammatory immunosuppressive that can decrease joint damage and disability in people with lupus, rheumatoid arthritis, and other conditions. In addition, Imuran has proven to clearly improve lupus affecting the liver and kidneys. Then he gave me the choice of one tablet of Imuran or 2-3 tablets daily of CellCept. Chose the Imuran but upon educating myself, am wondering if that was the best first choice. Had not heard of Plaquenil. It's all so confusing to a newbie. The prednisone did wonders for the pain and I am still on it so don't know how I'll know if Imuran is working. Learn about drug interactions between azathioprine oral and hydroxychloroquine oral and use the RxList drug interaction checker to check drug combinations. So it's worth taking some time to think about other possible causes. XBeen taking plaquenil for some 13 years now - seems to reduce the flairs but doesn't stop them. There are many possible triggers for a flare, & as lupus sufferers we are all different. Imuran plaquenil together Imuran Azathioprine Uses, Dosage, Side Effects., Treatmenmt for Lupus-Plaquenil and Imuran Plaquenil exfoliative dermatitisNew guidelines for plaquenil macuopathy 2018 pubmedHow quickly does plaquenil workPlaquenil drug assistance programPlaquenil side effects when stopping What it is Azathioprine or the brand name Imuran, is a drug that was originally developed to prevent organ rejection in people who had received a donor transplant. Currently, in addition to its anti-rejection properties, it is also being used more and more to treat autoimmune diseases like systemic lupus, dermatomyositis, vasculitis, rheumatoid arthritis and AZATHIOPRINE and Lupus - Kaleidoscope Fighting Lupus. Azathioprine oral and hydroxychloroquine oral Drug.. Hydroxychloroquine Indications, Side Effects, Warnings.. Thanks for taking the time to reply I'm taking Plaquenil for 4 years the Imuran Azathioprine spwas added during the summer. I do feel better today I did come up with the malar rash which is a sure sign that a flair is on the way but as I said I feel better today and the rash is going down. Maybe the Imuran is working. Feb 19, 2020 PLAQUENIL is not effective against chloroquine or hydroxychloroquine-resistant strains of Plasmodium species see CLINICAL PHARMACOLOGY - Microbiology. PLAQUENIL is not recommended for the treatment of malaria acquired in geographic areas where chloroquine resistance occurs or when the Plasmodium species has not been identified. Note This document contains side effect information about azathioprine. Some of the dosage forms listed on this page may not apply to the brand name Imuran. In Summary. Common side effects of Imuran include infection, leukopenia, and vomiting.