You may have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. Davis drug guide pdf hydroxychloroquine Topical hydroxychloroquine Malaria proguanil and chloroquine Hydroxychloroquine tonic water A patient with psoriatic arthritis developed a peripheral neuropathy while taking hydroxychloroquine and naproxen. Although it was initially suspected that hydroxychloroquine was responsible for the neuropathy, subsequent rechallenge with naproxen demonstrated that clinical and electrophysiologic findings were related to routine pharmacologic doses of naproxen. Treatment should be discontinued if hydroxychloroquine treatment is identified as the cause of any of these serious blood dyscrasias 2. Neurological and Neuromuscular Reactions. In New Zealand, there have been two reports of peripheral neuropathy associated with hydroxychloroquine use since 1 January 2010. Peripheral neuropathies arise from disorders associated specifically outside the central nervous system CNS and within the peripheral nervous system. 1 Symptoms of peripheral neuropathy include numbness, tingling, paresthesia pins and needles sensations, sensitivity to touch, or muscle weakness. [Multiple sclerosis (MS) and Myasthenia Gravis (MG) have their own forums below.]Fibromyalgia syndrome is a widespread musculoskeletal pain and fatigue disorder which generally occurs in the muscles, ligaments, and tendons the soft fibrous tissues in the body. This "Sanctuary" is a place for people of all spiritual beliefs and faiths to offer support and compassion to each other in the form of prayers, meditation, and expressions of spirituality. For Hashimotos thyroiditis (underactive thyroid), Graves disease (overactive thyroid), Lupus, Crohn's disease, all types of arthritis, and all other autoimmune diseases. Hydroxychloroquine and peripheral neuropathy Toxic neuropathies, Risks of Hydroxychloroquine Plaquenil and thinning outer nuclear layer of retinaPlaquenil and itchy eyes My understanding about Plaquenil is the doses taken for autoimmune disease is far less then that for Malaria, and even then the incident of neuropathy with malaria dosing is very low. I do know that eye damage from Plaquenil is extremely rare and most ophthalmologists tell me that they will never see a case.they still do bi-annual. Plaquenil causes and treats neuropathy? - NeuroTalk.. Neuropathy in the Cancer Patient Causes and Cures. Plaquenil and small fiber neuropathy - NeuroTalk Support.. Including our patient, there are 10 reported cases of HCQ neuromyotoxicity. Muscle biopsy consistently reveals curvilinear bodies and muscle fiber atrophy with vacuolar changes. Most cases manifest as insidious onset proximal myopathy that may be associated with peripheral neuropathy and cardiac myotoxicity. View detailed reports from patients taking plaquenil who experienced neuropathy peripheral. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. She was also prescribed 300 mg of hydroxychloroquine per day 200 mg–400 mg alternatively on every other day for eight months. On physical examination, severe myalgia and weakness of both arms and legs were noted. The neurological examination showed no evidence suggesting peripheral neuropathy.