This study is created by e Health Me based on reports of 57,706 people who have side effects when taking Plaquenil from Food and Drug Administration (FDA), and is updated regularly. On e Health Me, you can evaluate side effects and drug interactions from 16 million FDA reports. Does plaquenil loeer esr Aralen for malaria prophylaxis Hi! I think Plaquenil is the cause of my extreme fatigue too. I am not anemic at this time and I get exhausted just trying to get through the day. I have also been on Plaquenil about three months. All of my arthritis swelling and pain are gone, but the fatigue will not let up! Hope things change for you. When I started Plaquenil back in November last year, I had terrible headaches which started about 1/2 an hour after taking pills. It happened so consistently that I started taking tylenol when I would take it. I would lay down with an ice pack under my neck and darken the room. Plaquenil and Humira belong to different drug classes. Plaquenil is an antimalarial medication and Humira is an injectable protein. Side effects of Plaquenil and Humira that are similar include headache or stomach pain or cramps. You can also discuss your drugs with qualified professionals to ensure drugs are working to improve your health. The study is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). Headache (pain in head) has been reported by people with multiple sclerosis, rheumatoid arthritis, high blood pressure, depression, pain. The results are personalized to your gender and age (0-99 ). Plaquenil and headaches Medication Triggers in Autoimmune Migraineurs, Plaquenil and headaches DailyStrength Plaquenil side effects mouth soresAdverse effects of plaquenil menstrual cyclePlaquenil oct flying saucerChloroquin mechanism Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Long-Term Side Effects of Plaquenil for Rheumatoid.. Plaquenil vs. Humira Prescription Treatment for Rheumatoid.. Plaquenil – RheumInfo. PLAQUENIL brand-name is fantastic, however the generic Hydroxychloroquine is awful. After another two months on the drug I experienced serious headaches and my Rhumatologist reduced the dose. Confused whether the headaches are lupus headaches vs migraines or both? Understanding the causes and symptoms can help you decide the right treatment options. #LupusWarriors might experience the dreaded lupus fog bringing the mind and body often to a confused state and difficulty remembering potentially crucial parts of their life. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more.