Inhibition of protein synthesis is also observed, evidently as a secondary effect. Inhibition of DNA replication is proposed as a general mechanism of the antimicrobial action of chloroquine. Hydroxychloroquine action Plaquenil curly hair Chloroquine DescriptionChloroquine - Clinical PharmacologyIndications and Usage For ChloroquineContraindicationsWarningsPrecautionsAdverse ReactionsOverdosageChloroquine Dosage and AdministrationHow Is Chloroquine SuppliedReferences Research on the mechanism of chloroquine and how the parasite has acquired chloroquine resistance is still ongoing, as other mechanisms of resistance are likely. citation needed Other agents which have been shown to reverse chloroquine resistance in malaria are chlorpheniramine, gefitinib, imatinib, tariquidar and zosuquidar. Antiviral Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. Thank you for your interest in spreading the word about Science. Chloroquine mode of action malaria Chloroquine Mechanism of drug action and resistance in., Chloroquine - Wikipedia Hydroxychloroquine in lupus pregnancyVision loss from plaquenilChloroquine phosphate child's dosage malaria prophylaxisPlaquenil and multivitamins The clinical usefulness of chloroquine, and in some recent cases of quinine as well, has been much reduced by the evolution and spread of chloroquine resistant malaria parasites. The mechanism of resistance involves a reduced accumulation of the drug, although again the mechanism involved is controversial. Chloroquine mechanism of drug action and resistance in.. Aralen chloroquine Malaria Drug Side Effects & Dosage. Mode of Action of Chloroquine - Malaria Home Page. Chloroquine works best when you take it on a regular schedule. For example, if you are taking it once a week to prevent malaria, it is best to take it on the same day of each week. Make sure that you do not miss any doses. If you have any questions about this, check with your doctor. By Angela Baldwin What do malaria and COVID-19 have in common? On the surface, not much. But according to early research, an old malaria drug called chloroquine might also work for the new coronavirus. Could a decades-old malaria drug work to treat COVID-19? Elon Musk seems to think so, recently tweeting that it “might be worth Malaria infection associated with travel. Center for Global Health Division of Parasitic Diseases and Malaria. Who can take chloroquine? Chloroquine can be prescribed to adults and children of all ages. It can also be safely taken by pregnant. women and nursing mothers. Who should not take chloroquine? People with psoriasis should not take.