Chloroquine related chloroform

Discussion in 'Health Canada Drug Database' started by chiffa_cff, 06-Mar-2020.

  1. sibcom User

    Chloroquine related chloroform


    If you’re more interested in the chemistry, rather than the action of the scene mentioned above, then this question must have popped up in your head at some point: does chloroform (the liquid that they soak the rag in) really knock one out that quickly? Chloroform is a colorless, sweet-smelling organic compound with the IUPAC name Trichloromethane and formula CHCl3.

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    Chloroquine phosphate has a bitter taste; it is slowly discoloured by light. Chloroquine phosphate may exist in 2 polymorphic forms differing in melting temperature, one of which melts at about 194°C, the other at about 215°C; mixtures of the 2 forms melt between 194°C and 215°C. Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances of hypersensitivity reactions which can be accompanied by hepatitis and mild jaundice. Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA.

    The structural formula of chloroform is given below: As mentioned earlier, chloroform is a highly volatile liquid that has been widely used for its anesthetic properties throughout history. It is a dense liquid with a tetrahedral molecular geometry with C3 symmetry.

    Chloroquine related chloroform

    How Does Chloroform Work To Knock You Off? Science ABC, Quinine C20H24O2N2 - PubChem

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    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Chloroquine phosphate, USP is a 4-aminoquinoline compound for oral administration. It is a white crystalline powder; odorless; has a bitter taste, and is discolored slowly on exposure to light. It is freely soluble in water, practically insoluble in alcohol, in chloroform and in ether. Chloroquine phosphate, USP is an antimalarial and. Chloroquine phosphate tablets should not be used in these conditions unless the benefit to the patient outweighs the potential risks. Usage in Pregnancy Usage of Chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus.

     
  4. Andrei Z Well-Known Member

    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Could an old malaria drug help fight the new coronavirus? Home Chloroquine Department of Defence Aralen - Prescription Drug Information.
     
  5. oleg1968 New Member

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