I know I had never heard of it until my rheumatologist said that is what I have...along w/osteoarthritis and fibromyalgia. My blood tests are negative for RF but my CRP test was above normal. Ai Yi Yi Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells (these are messengers for your immune system, if you will) from interacting with your T-Cells (a special type of white blood cell which through a convoluted and boring process, causes inflammation when an infection is found, and these basically malfunction with inflammatory disorders). So, he started me on 400 mg of Plaquenil a day and he just upped it to 600 mg a day. As I said previously, my Rheumatologist now says it is inflammatory osteoarthrits. Why am I taking Plaquenil, which does help tremedously BTW, if I don't have RA or Lupus. This "dendritic deactivation" (I made that phrase up) helps reduce your immune system being silly and inflaming your joints. Recommended dosage of plaquenil Plaquenil and liver enzymes Can hydroxychloroquine cause erectile dysfunction Sep 18, 2007 Answer. Plaquenil does not need to be stopped for surgery so it can be restarted after the procedure. Although in studies Celebrex does not cause increased bleeding, unilke other older NSAIDs, some surgeons still advise to stop it to be safe. In general, Celebrex can be restarted the day after the procedure once the risk of bleeding is over. DAILY MEDICATION USE AND YOUR UPCOMING SURGERY PLEASE take time to thoroughly read this information. It is VERY IMPORTANT for you to know what medications you are taking and to understand what to do about your medications as your surgery date approaches. PLEASE inform our nurses if any medication you take is not on the following list. Find information about common, infrequent and rare side effects of Plaquenil Oral. My sister was dx'd with Inflammatory Arthritis and Plaquenil sent her into remission some years ago now. I also take meds for high bp, asthma and high cholesterol. Plaquenil and knee replacement Plaquenil and Orencia" Osteoarthritis Community - Support Group, DAILY MEDICATION USE AND YOUR UPCOMING SURGERY Hydroxychloroquine sun pharmaceuticalsAdverse effects of hydroxychloroquineCan i just stop taking hydroxychloroquinePlaquenil manufacturer Comment Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells. Plaquenil oral Reviews and User Ratings Effectiveness, Ease.. Common and Rare Side Effects for Plaquenil Oral. Perioperative Management of Medications Used in the.. Nov 29, 2010 Does anyone know why you had to stop Plaquenil before surgery? I'm just curious because I had a partial knee replacement when I was on Plaquenil and wasn't advised to stop it - or any of the other meds I was on. Take care - Scottie Hydroxychloroquine Plaquenil is commonly used for treating joint pain in Sjögren’s syndrome patients, based in part on its efficacy in treating the joint pain of patients with systemic lupus erythematosus and rheumatoid arthritis. Knee joint replacement is found among people who take Rituxan, especially for people who are female, 40-49 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Systemic lupus erythematosus.