It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine-induced pigmentation Sarafen and plaquenil Plaquenil toxicity ocular Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. The primary antimalarial medication associated with hemolytic anemia in G6PDH deficient patients is primaquine, an 8‐aminoquinoline. HCQ and chloroquine are 4‐aminoquinolines, and have not been reported to cause hemolysis in G6PDH‐deficient individuals. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Does plaquenil cause anemia Common and Rare Side Effects for Plaquenil Oral, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Hydroxychloroquine cream side effectsPlaquenil reviews for sjogren& 39Fatcs on chloroquineDoes plaquenil increase risk of infection Feb 19, 2020 What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Examination of Hydroxychloroquine Use and Hemolytic Anemia.. Plaquenil and Anemia - General Discussion - Life With Lupus. This causes blood loss, resulting in anemia. If your anemia is severe enough, it may be treated with a blood transfusion. This will boost both your red blood cell count and your iron levels. NSAIDs can also damage the liver, where iron from the food you eat is stored and released for later use. Management of macrocytosis consists of finding and treating the underlying cause. In the case of vitamin B-12 or folate deficiency, treatment may include diet modification and dietary supplements or injections. If the underlying cause is resulting in severe anemia, you might need a blood transfusion. Anemia is most often caused by low iron levels in the blood. Without iron, red blood cells begin to drop in levels of hemoglobin, which carries oxygen from the lungs to the rest of the body. Another cause of anemia is a deficiency in vitamin B12. Other issues that can inhibit the body’s production of red blood cells, resulting in anemia, include kidney disease, chronic inflammation, leukemia, and inherited conditions.