Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine risk Eye problems caused by plaquenil INTRODUCTION Hydroxychloroquine HCQ is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus SLE. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hi - i have been on Plaquenil for 28 yrs with mild SLE. Recently dropped my dosage in half, and ended up with tinitus in one ear.anyone got any thoughts/advice? thanks Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil for sle Hydroxychloroquine 200 mg Tablets Generic Plaquenil, Hydroxychloroquine Side Effects, Dosage, Uses, and More El plaquenil engordaBilling oct for plaquenilChloroquine primaquine combinationRetinal half life of plaquenil Anti-inflammatories are the most common drugs used to treat lupus, particularly symptoms such as fever, arthritis or pleurisy, which generally improve within several days of beginning treatment. For many people with lupus, an anti-inflammatory drug may be the only medication they need to control their lupus. Medications used to treat lupus Lupus Foundation of America. Tinnitus and SLE, Plaquenil? Hi - i have been on. - LUPUS UK. Plaquenil. A medication for Lupus. Hydroxychloroquine is an appropriate agent to address milder systemic manifestations of systemic lupus erythematosus SLE such as arthritis and pericarditis, and it can act as a glucocorticoid-sparing agent. Some of the medications that may interact with Plaquenil include Arava lefunomide. Aurolate gold sodium thiomalate. Aubagio. Ferriprox. Mellaril. Sabril. Initial dose for the treatment of SLE, 400mg×2/day, is about the dose used in one of the studies above. Maintenance dose would keep the serum concentration constant. Assuming HCQ is effective, it would most definitely be protective in doses used in SLE patients.