They play a very important role, serving as the body’s wiring system. Their main task is to carry messages between the brain and the rest of the body. Primaquine and chloroquine are drugs used in the treatment of Plaquenil peripheral neuropathy One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. A rare form of nerve disease in patients with rheumatoid arthritis that causes numbness and/or tingling is neuropathy. Neuropathy is nerve damage that in people with rheumatoid arthritis can result from inflammation of blood vessels vasculitis. Vasculitis is not common, but it is very dangerous. They can signal a condition called peripheral neuropathy, or nerve damage. Lupus is an autoimmune condition that causes the immune system to attack normal, healthy cells and tissue. About 10 to 15 percent of people with lupus experience symptoms of peripheral neuropathy. To help carry the messages properly, each nerve has small fibers bundled inside it, covered by an outer layer that insulates and protects them. While some nerves are responsible for carrying messages from the brain to the muscles in order to make the body move, there are other nerves that send messages about pain, pressure, or temperature from the body to the brain. Can plaquenil cause nerve damage Plaquenil and small fiber neuropathy - NeuroTalk Support., Rheumatoid Arthritis 17 Signs of Serious Complications Is chloroquine a quinolineG6pd and hydroxychloroquineDoes hydroxychloroquine thin blood Can Plaquenil cause Optic Nerve Damage? Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Can Plaquenil cause Optic Nerve Damage? - Treato. Lupus and Nerve Damage -. Will you have Peripheral neuropathy with Plaquenil - eHealthMe. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 How to use Plaquenil Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. Blurred vision While taking this medication, use caution when driving or operating machinery, since hydroxychloroquine can cause blurring of vision. If your vision blurs, call your doctor. Eye damage Irreversible damage to the retina of the eye has occurred for some people who take long-term or high-dosage treatment with hydroxychloroquine. Eye damage is more likely to occur if recommended doses are exceeded.