and other countries, cow's milk and plant-derived milk substitutes are fortified with vitamin D, as are many breakfast cereals. Dietary recommendations typically assume that all of a person's vitamin D is taken by mouth, as sun exposure in the population is variable and recommendations about the amount of sun exposure that is safe are uncertain in view of the skin cancer risk. Is hydroxychloroquine an immunosuppressive Plaquenil and agep The duration of treatment was also associated with the level of vitamin D P 0.0001, and control patients presented significantly higher vitamin D levels than patients receiving doxycycline-hydroxychloroquine, whether for less than or for more than 3 months P 0.0001 and P 0.0001, respectively Fig. 1b. The study is based on hydroxychloroquine sulfate and ergocalciferol the active ingredients of Plaquenil and Vitamin d, respectively, and Plaquenil and Vitamin d the brand names. Other drugs that have the same active ingredients e.g. generic drugs are not considered. Vitamin D is primarily produced in the skin by the action of sunlight, and possibly patients receiving doxycycline-hydroxychloroquine treatment are not exposed to sunlight because of photosensitization and thus present vitamin D deficiency. We propose that patients with long-term doxycycline-and-hydroxychloroquine treatment should be regularly tested, and in cases of vitamin D deficiency, treatment with a vitamin D supplement should be added. A protein enzyme must hydroxylate it to convert it to the active form. As vitamin D can be synthesized in adequate amounts by most mammals exposed to sufficient sunlight, it is not an essential dietary factor, although not technically a vitamin. Vitamin D from the diet, or from skin synthesis, is biologically inactive. Hydroxychloroquine with vit d Hydroxychloroquine Blood Levels in SLE Clarifying dosing controversies., Plaquenil and Vitamin d drug interactions - eHealthMe Plaquenil hot flashesPlaquenil treatment lyme diseaseAdverse effects of chloroquineCan plaquenil give you lymphoma Here, we report the case of two patients in whom conventional treatment was unsuccessful but who responded to hydroxychloroquine and high-dose vitamin D replacement therapy. To the best of our knowledge, this is the first description of successful treatment for immune thrombocytopenia with high-dose vitamin D and hydroxychloroquine. Refractory immune thrombocytopenia successfully treated with high-dose.. Vitamin D and Prolonged Treatment with Photosensitivity.. Vitamin d and Hydroxychloroquine sulfate drug interactions.. Anyhow, I was researching to see if Plaquenil interferes with any vitamins or supplements since I take quite a few and read several articles on how Plaquenil depletes Vit D and Calcium. Well, not such good news since I am Vit D deficient only borderline now with supplementation and just found out I'm hypoparathyroid. Provides a summary of interactions with vitamins, herbs, and food Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America.