Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Natural substitute for plaquenil for discoid lupus Plaquenil generic contraindicated RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Common side effects include headache; dizziness; loss of appetite; nausea; diarrhea; stomach pain; vomiting; nervousness; rash; Tell your doctor if you have any side effect that bothers you or does not go away. These are not all the possible side effects Plaquenil. For more information, ask your doctor or pharmacist. Side Effects. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or other. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil side effects long term Hydroxychloroquine Plaquenil, Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol. Plaquenil cardiotoxicityPlaquenil use in patientsPlaquenil painful muscle spasmsHydroxychloroquine canadaPlaquenil retinal detachment Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Rx Side Effects New Plaquenil Guidelines and More - American.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs. Eye problems is one of the more serious side effects from plaquenil that you hear people talk about. My rheumy says it's mostly long term that causes the eye problems but recommends me to keep regular eye exams and make them aware that I'm on it. Plaquenil. Uses. Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of. Side Effects. Precautions. Interactions.