Chloroquine treatment of amoebic liver abscess

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  1. Mikerr New Member

    Chloroquine treatment of amoebic liver abscess


    After completion of treatment with tissue amebicides, administer luminal amebicides for eradication of the asymptomatic colonization state. Failure to use luminal agents can lead to relapse of infection in approximately 10% of patients.

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    Treated with chloroquine were also given dii­ odohydroxquin, 650 mg three times daily for 20 days, beginning after clinical improvement in the symptoms of liver abscess. For final diagno­ sis of amoebic liver abscess, requirements, in addition to the clinical picture, were a filling Chloroquine and metronidazole were compared in a randomized trial for the treatment of amoebic liver abscess in 36 patients. An additional 30 patients were treated without randomization. Chloroquine was given according to the standard protocol at Los Angeles County-University of Southern California Medical Center, which is 500 mg daily for 10 weeks, whereas metronidazole was given in a dose of. Thank you for your interest in spreading the word about The BMJ. NOTE We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail.

    The details on tissue and luminal amebicidal agents are discussed in Medication. In general, metronidazole, tinidazole, emetine, and dehydroemetine are active in invaded tissues; chloroquine is active only in the liver; tetracycline acts on the bowel wall; and diloxanide furoate, paromomycin, and iodoquinol are luminal agents only.

    Chloroquine treatment of amoebic liver abscess

    Chloroquine in the Treatment of Amoebic Liver Abscess, Comparison of Metronidazole and Chloroquine for the Treatment of.

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  3. The second line drugs in treatment of amoebic liver abscess include emetine and chloroquine. Combination of more than one drug is not superior to use of single drug as there is no evidence at present of the superiority of combining two or more anti amoebic drugs. The treatment regimen for amoebic liver abscess should include use of luminal.

    • Treatment of Amebic Liver Abscess.
    • Chloroquine in the Treatment of Amoebic Liver Abscess The BMJ.
    • REFRACTORY AMEBIC ABSCESS OF THE LIVER TREATED WITH CHLOROQUINE.

    Rarely, when patients of amoebic liver abscess are vomiting, injection chloroquine can be used in a dose of 0.3–0.6 G. base in 24 hours not exceeding 0.9 G. Chloroquine given alone is a safer drug than emetine in amoebic liver abscess, but unfortunately the relapse rate is almost 25%. Comparison of Metronidazole and Chloroquine for the Treatment of Amoebic Liver Abscess A controlled trial Harry G. Cohen, M. D. Telfer B. Reynolds, M. D. Department of Medicine, University of Southern California School of Medicine and Los Angeles County-University of Southern California, Medical Center, Los Angeles, California Department of. Alternative treatment of amebic liver abscess involves the use of emetin - 1 mg / kg per day once intramuscularly no more than 60 mg / day for 4-6 days chloroquine base - 600 mg per day for 2 days, then 300 mg for 2-3 weeks - simultaneously or immediately after the completion of the course of emetine.

     
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