So whenever something goes wrong inside, it eventually starts reflecting on the skin. One such sign is hyperpigmentation, a sign from your skin that all is not well within your body. Hydroxychloroquine and kidney Hydroxychloroquine dosage rheumatoid arthritis Hydroxychloroquine HCQ-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy 1. A 32-year-old woman presented with a 1.5-year history of symmetric polyarthritis, positive rheumatoid factor, and anticyclic citrullinated peptide antibody, without erosive joint changes. Drug-induced skin pigmentation accounts for 10–20% of all cases of acquired hyperpigmentation. Pigmentation may be induced by a wide variety of drugs; the main ones implicated include non-steroidal anti- inflammatory drugs NSAIDs, phenytoin, antimalarials, amiodarone, antipsychotic drugs, cytotoxic drugs, tetracyclines, and heavy metals. I have been on it for 8 months straight this time joint pain has improved. I now have hyperpigmentation a darkening or tanned effect on my face and forearms that showed up several months ago and it looks similar to Melasma, I have researched and found this is a side effect of plaquenil. It is mainly caused due to the overproduction of melanin, the pigment that gives skin its colour. Hyperpigmentation is a dermatological condition when the getting discoloured and darkened in places. Plaquenil cause hyperpigmentation Hydroxychloroquine-Induced Pigmentation in Patients With Systemic Lupus., Drug-induced hyperpigmentation DermNet NZ Plaquenil and pregnancy categoryPlaquenil toxicity dosageHydroxychloroquine icd 10 code Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. OBJECTIVE To describe the clinical features and outcome of hydroxychloroquine HCQ-induced pigmentation in patients with systemic lupus erythematosus SLE. Hydroxychloroquine-induced pigmentation in patients with.. Plaquenil side effect hyperpigmentation. Hydroxychloroquine-Associated Hyperpigmentation Mimicking.. PLAQUENIL has been shown to cause severe hypoglycemia including loss of consciousness that could be life threatening in patients treated with or without antidiabetic medications see DRUG INTERACTIONS and ADVERSE REACTIONS. Patients treated with PLAQUENIL should be warned about the risk of hypoglycemia and the associated clinical signs and. Dec 15, 2017 It is mainly caused due to the overproduction of melanin, the pigment that gives skin its colour. Although it is usually associated with ageing, hyperpigmentation may usually point towards an underlying health condition. Here are some of the health problems that could cause hyperpigmentation. Health conditions that can cause hyperpigmentation Skin discolouration or hyperpigmentation is a sign of underlying health problems. Switch to हिंदी.