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    Seek immediate medical attention if you take too much sertraline, as an overdose of sertraline can cause rapid heartbeat, seizures, hair loss, irregular sex drive or ability, insomnia, hallucinations, fainting, confusion, tremor, agitation, vomiting, nausea, drowsiness, dizziness, fatigue, diarrhea, shaking of part of the body, and coma. zithromax 5 day dose pack Pediatric Intensive Care Unit, Centro Hospitalar de São João, EPE, Alameda Prof. Serotonin syndrome is a potentially life-threatening drug effect. Hernâni Monteiro, 4200-319 Porto, Portugal Received 11 October 2013; Accepted 2 December 2013Academic Editors: C. It may be misdiagnosed because it has mostly been reported in adults. An 8-year-old girl with behavioral problems and medicated with risperidone and sertraline was admitted in the emergency department after she had taken voluntarily 1500 mg of sertraline (50 mg/kg). This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. At admission, she had marked agitation, visual hallucinations, diaphoresis, flushing, and tremor. She also showed generalized rigidity and involuntary movements. She was treated with fluids and iv diazepam, midazolam, clemastine, and biperiden. As the patient presented a severe insomnia and a progressive rhabdomyolysis, she was transferred to pediatric intensive care unit (ICU), where she was under treatment with cyproheptadine, mechanical ventilation, and muscular paralysis for 11 days. She was discharged from hospital a few days later with no neurological sequelae. Serotonin syndrome is still not well recognized by physicians.

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    The study - conducted in nonhuman primates with brain structures and functions similar to those of humans - found that the antidepressant sertraline, a selective serotonin reuptake inhibitor (SSRI) marketed as Zoloft, significantly increased the volume of one brain region in depressed subjects but decreased the volume of two brain areas in non-depressed subjects. "These observations are important for human health because Zoloft is widely prescribed for a number of disorders other than depression," said Carol A. D., professor of pathology-comparative medicine at Wake Forest Baptist and lead author of the study, published in the current online issue of the journal Neuropharmacology. In the study, 41 middle-aged female monkeys were fed a diet formulated to replicate that consumed by many Americans for 18 months, during which time depressive behavior in the animals was recorded. Female monkeys were chosen for this study because depression is nearly twice as common in women as men and the use of antidepressants is most common in women ages 40 to 59. After the 18-month pre-study phase, the monkeys were divided into two groups balanced for body weight, body mass index and depressive behavior. For the next 18 months, 21 monkeys received sertraline in daily doses comparable to those taken by humans while a group of 20 received a placebo. This treatment regimen is analogous to a human taking an antidepressant for approximately five years. Contact a suicide hotline if you need someone to talk to. If you have a friend in need of help, please encourage that person to contact a suicide hotline as well.- Worldwide In general, if you're outside the US, numbers for your country are here: .pass_color_to_child_links a.u-margin-left--xs.u-margin-right--sm.u-padding-left--xs.u-padding-right--xs.u-relative.u-absolute.u-absolute--center.u-width--100.u-flex-inline.u-flex-align-self--center.u-flex-justify--between.u-serif-font-main--regular.js-wf-loaded .u-serif-font-main--regular.amp-page .u-serif-font-main--regular.u-border-radius--ellipse.u-hover-bg--black-transparent.u-hover-bg--black-transparent:hover. Content Header .feed_item_answer_user.js-wf-loaded .

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